Technology

The Personal Glucose Meter (PGM) is a widely available and proven medical device that is used by millions of diabetics around the globe. Today’s glucose meter is the culmination of over 30 years of engineering and development efforts to make it do one thing extraordinarily well: measure blood glucose levels anytime, anywhere. At GlucoSentient, we have developed a powerful technology that is transforming the PGM into a device that is capable of quantitatively and conveniently detecting other non-glucose targets. This is made possible by our patent pending technology that translates the amount of non-glucose target to glucose. The amount of glucose is then measured by the PGM. The technology is robust and widely applicable, including heavy metal ions (environmental monitoring), small molecules (drug monitoring, drugs-of-abuse tests), protein markers (immunoassay diagnostics) and nucleic acid (molecular diagnostics) quantification.

Recent Advances

Using personal glucose meters and functional DNA sensors to quantify a variety of analytical targets

Portable and Quantitative Detection of Protein Biomarkers and Small Molecular Toxins Using Antibodies and Ubiquitous Personal Glucose Meters

Using Commercially Available Personal Glucose Meters for Portable Quantification of DNA

An invasive DNA approach toward a general method for portable quantification of metal ions using a personal glucose meter

Promising future in mHealth

In a time when mobile phones are getting more and more powerful, it’s no longer far reaching to assume that they will become the mobile consoles for our health. There have already been applications using mobile phones for measuring vital signs such as heart rate and blood pressure. Recently, several mobile phone glucose meters have been granted FDA approval. GlucoSentient’s technology turns a  smartphone into a multi-analyte remote sensing device.

Quotes

“There is real genius in the idea of leveraging the ultracheap, ultrafast, high-precision glucose-sensing capabilities of PGMs to analyze other analytes.  The word ‘innovative’ is often used, but it should be reserved for ideas like this one.”

Reginald M. Penner, University of California, Irvine [C&EN]

“It is the engineering and development work done in their pairing, and showing that such a pairing can potentially have a huge impact in existing markets, that is surprising, novel, and extremely ­worthwhile.”

 Andrew Ellington, University of Texas Austin

“… PDAs and smartphones will become personal healthcare assistants capable of receiving vital signs and even body fluid samples for analysis and transmittal of results. Wherever patients are in the world, they will be able to connect with their physicians. And their doctors, in turn, will be able to practice medicine virtually anywhere and at anytime, with instant access to the information and systems they need—right at their thumbs.”

  Burrill Consumer Digital Health Meeting